Dental OSCE (Objective Structured Clinical Examination) Practice Exam

What is a characteristic feature of hereditary benign intraepithelial dyskeratosis (HBID)?

1. Genetic mutation

2. Abnormal mitosis

3. Inflammatory response

4. Cyst formation

The correct answer is: Abnormal mitosis

Hereditary benign intraepithelial dyskeratosis (HBID) is characterized by abnormal keratinization of the epithelium. The condition is often associated with abnormal mitosis, meaning that the cellular division process is disrupted, leading to atypical epithelial cell formation. This abnormal mitosis can result in the formation of lesions that may present in the oral cavity, typically affecting the mucous membranes. In contrast, while genetic mutations can be present in various hereditary conditions, HBID is more specifically recognized for its abnormal cellular processes rather than a specific mutation. Inflammation may occur in response to the lesions, but it is not the primary feature of HBID itself. Cyst formation is also not a characteristic of this condition, as HBID primarily involves keratinization rather than the development of cystic structures. Thus, the key aspect of HBID is the abnormal mitosis leading to its distinctive epithelial changes.